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Substitution of MDAI for the discriminative stimulus effects of MDMA, cocaine, methamphetamine, or DOM in rats. The upper panel shows percentage of total responses on the drug-appropriate lever as a function of log dose of MDAI. The lower panel shows rate of responding in responses per second (r/s). Data are from groups of 6 rats. Ctrl indicates average of responding to vehicle (0.9% saline) and drug controls. * indicates response rate different from vehicle control (p < 0.05).
