Table 1.
Baseline demographics by log-transformed pro-NT quartiles.
| Characteristic | All (N=3439) |
Quartile 1 (N=860) |
Quartile 2 (N=860) |
Quartile 3 (N=859) |
Quartile 4 (N=860) |
p-value |
|---|---|---|---|---|---|---|
| Age | ||||||
| Mean±SD (N) | 59.19±9.76 (3439) | 59.20±10.10 (860) | 59.13±9.74 (860) | 60.04±9.49 (859) | 58.39±9.65 (860) | 0.006 |
| Median (Q1,Q3) | 58.70 (51.95,66.71) | 58.70 (51.39,67.23) | 58.72 (51.83,66.27) | 59.86 (52.95,67.51) | 57.45 (51.59,65.62) | |
| Range (min,max) | (29.67,86.75) | (32.05,86.75) | (33.51,85.47) | (34.66,85.55) | (29.67,82.63) | |
| Male | 47.1% (1620/3439) | 45.3% (390/860) | 47.3% (407/860) | 47.3% (406/859) | 48.5% (417/860) | 0.626 |
| BMI | ||||||
| Mean±SD (N) | 27.91±5.14 (3430) | 27.30±4.74 (856) | 28.11±5.22 (859) | 27.92±5.33 (858) | 28.30±5.19 (857) | <.001 |
| Median (Q1,Q3) | 27.18 (24.40,30.54) | 26.76 (23.84,29.88) | 27.36 (24.67,30.69) | 26.82 (24.36,30.60) | 27.65 (24.80,30.72) | |
| Range (min,max) | (16.59,54.33) | (17.41,47.25) | (17.57,53.01) | (16.59,54.33) | (17.21,53.42) | |
| Waist Girth | ||||||
| Mean±SD (N) | 38.42±5.35 (3407) | 37.82±5.15 (854) | 38.61±5.42 (852) | 38.33±5.43 (849) | 38.94±5.32 (852) | <.001 |
| Median (Q1,Q3) | 38.25 (35.00,41.50) | 37.50 (34.50,41.00) | 38.50 (35.00,41.75) | 38.00 (34.50,41.50) | 38.88 (35.50,42.00) | |
| Range (min,max) | (23.75,60.00) | (24.25,56.75) | (25.00,60.00) | (23.75,58.25) | (25.75,59.50) | |
| Total cholesterol/HDL Ratio | ||||||
| Mean±SD (N) | 4.41±1.75 (3431) | 4.35±1.60 (859) | 4.40±1.46 (859) | 4.38±1.59 (856) | 4.51±2.26 (857) | 0.253 |
| Median (Q1,Q3) | 4.17 (3.30,5.20) | 4.09 (3.26,5.15) | 4.22 (3.33,5.28) | 4.13 (3.30,5.16) | 4.23 (3.33,5.24) | |
| Range (min,max) | (1.50,52.06) | (1.67,18.62) | (1.83,13.85) | (1.50,15.90) | (1.65,52.06) | |
| Calculated LDL | ||||||
| Mean±SD (N) | 127.14±33.63 (3373) | 126.44±33.40 (843) | 128.95±32.97 (847) | 126.17±32.52 (841) | 126.99±35.55 (842) | 0.316 |
| Median (Q1,Q3) | 125.20 (104.20,147.80) | 124.00 (103.40,146.60) | 128.00 (106.80,149.60) | 124.80 (104.40,147.00) | 124.40 (102.80,148.00) | |
| Range (min,max) | (30.00,355.00) | (30.00,261.60) | (31.40,301.00) | (31.60,258.80) | (39.20,355.00) | |
| Smoker | 15.3% (526/3439) | 11.6% (100/860) | 14.1% (121/860) | 15.9% (137/859) | 19.5% (168/860) | <.001 |
| Number of drinks per week | ||||||
| Mean±SD (N) | 5.09±7.72 (3436) | 5.56±7.91 (858) | 5.32±8.09 (860) | 4.63±7.22 (859) | 4.85±7.63 (859) | 0.048 |
| Median (Q1,Q3) | 2.00 (0.00,7.00) | 2.00 (0.00,8.00) | 2.00 (0.00,7.00) | 2.00 (0.00,7.00) | 2.00 (0.00,7.00) | |
| Range (min,max) | (0.00,85.00) | (0.00,57.00) | (0.00,85.00) | (0.00,54.00) | (0.00,70.00) | |
| Systolic Blood Pressure | ||||||
| Mean±SD (N) | 128.44±18.80 (3439) | 127.91±19.22 (860) | 128.14±18.13 (860) | 128.33±18.24 (859) | 129.37±19.56 (860) | 0.386 |
| Median (Q1,Q3) | 126.00 (115.00,139.00) | 125.00 (114.00,138.00) | 126.00 (115.00,138.00) | 126.00 (116.00,140.00) | 127.00 (115.00,140.00) | |
| Range (min,max) | (77.00,236.00) | (77.00,236.00) | (87.00,203.00) | (91.00,212.00) | (85.00,217.00) | |
| Antihypertensive Medication Use | 28.1% (963/3427) | 25.2% (216/858) | 28.6% (245/858) | 29.2% (249/853) | 29.5% (253/858) | 0.169 |
| Diabetes | 9.9% (340/3435) | 5.5% (47/860) | 9.7% (83/859) | 11.1% (95/857) | 13.4% (115/859) | <.001 |
| Prevalent Cancer | 6.1% (210/3439) | 6.4% (55/860) | 6.2% (53/860) | 5.4% (46/859) | 6.5% (56/860) | 0.748 |
| Prevalent Breast Cancer | 1.4% (49/3439) | 1.6% (14/860) | 1.2% (10/860) | 1.3% (11/859) | 1.6% (14/860) | 0.789 |
| Characteristic |
All (N=3439) |
Quartile 1 (N=860) |
Quartile 2 (N=860) |
Quartile 3 (N=859) |
Quartile 4 (N=860) |
p-value |
| Age | ||||||
| Mean±SD (N) | 59.19±9.76 (3439) | 59.20±10.10 (860) | 59.13±9.74 (860) | 60.04±9.49 (859) | 58.39±9.65 (860) | 0.006 |
| Median (Q1,Q3) | 58.70 (51.95,66.71) | 58.70 (51.39,67.23) | 58.72 (51.83,66.27) | 59.86 (52.95,67.51) | 57.45 (51.59,65.62) | |
| Range (min,max) | (29.67,86.75) | (32.05,86.75) | (33.51,85.47) | (34.66,85.55) | (29.67,82.63) | |
| Male | 47.1% (1620/3439) | 45.3% (390/860) | 47.3% (407/860) | 47.3% (406/859) | 48.5% (417/860) | 0.63 |
| BMI | ||||||
| Mean±SD (N) | 27.91±5.14 (3430) | 27.30±4.74 (856) | 28.11±5.22 (859) | 27.92±5.33 (858) | 28.30±5.19 (857) | <0.001 |
| Median (Q1,Q3) | 27.18 (24.40,30.54) | 26.76 (23.84,29.88) | 27.36 (24.67,30.69) | 26.82 (24.36,30.60) | 27.65 (24.80,30.72) | |
| Range (min,max) | (16.59,54.33) | (17.41,47.25) | (17.57,53.01) | (16.59,54.33) | (17.21,53.42) | |
| Waist Girth | ||||||
| Mean±SD (N) | 38.42±5.35 (3407) | 37.82±5.15 (854) | 38.61±5.42 (852) | 38.33±5.43 (849) | 38.94±5.32 (852) | <.001 |
| Median (Q1,Q3) | 38.25 (35.00,41.50) | 37.50 (34.50,41.00) | 38.50 (35.00,41.75) | 38.00 (34.50,41.50) | 38.88 (35.50,42.00) | |
| Range (min,max) | (23.75,60.00) | (24.25,56.75) | (25.00,60.00) | (23.75,58.25) | (25.75,59.50) | |
| Total cholesterol/HDL Ratio | ||||||
| Mean±SD (N) | 4.41±1.75 (3431) | 4.35±1.60 (859) | 4.40±1.46 (859) | 4.38±1.59 (856) | 4.51±2.26 (857) | 0.25 |
| Median (Q1,Q3) | 4.17 (3.30,5.20) | 4.09 (3.26,5.15) | 4.22 (3.33,5.28) | 4.13 (3.30,5.16) | 4.23 (3.33,5.24) | |
| Range (min,max) | (1.50,52.06) | (1.67,18.62) | (1.83,13.85) | (1.50,15.90) | (1.65,52.06) | |
| Calculated LDL | ||||||
| Mean±SD (N) | 127.14±33.63 (3373) | 126.44±33.40 (843) | 128.95±32.97 (847) | 126.17±32.52 (841) | 126.99±35.55 (842) | 0.32 |
| Median (Q1,Q3) | 125.20 (104.20,147.80) | 124.00 (103.40,146.60) | 128.00 (106.80,149.60) | 124.80 (104.40,147.00) | 124.40 (102.80,148.00) | |
| Range (min,max) | (30.00,355.00) | (30.00,261.60) | (31.40,301.00) | (31.60,258.80) | (39.20,355.00) | |
| Smoker | 15.3% (526/3439) | 11.6% (100/860) | 14.1% (121/860) | 15.9% (137/859) | 19.5% (168/860) | <0.001 |
| Number of drinks per week | ||||||
| Mean±SD (N) | 5.09±7.72 (3436) | 5.56±7.91 (858) | 5.32±8.09 (860) | 4.63±7.22 (859) | 4.85±7.63 (859) | 0.05 |
| Median (Q1,Q3) | 2.00 (0.00,7.00) | 2.00 (0.00,8.00) | 2.00 (0.00,7.00) | 2.00 (0.00,7.00) | 2.00 (0.00,7.00) | |
| Range (min,max) | (0.00,85.00) | (0.00,57.00) | (0.00,85.00) | (0.00,54.00) | (0.00,70.00) | |
| Systolic Blood Pressure | ||||||
| Mean±SD (N) | 128.44±18.80 (3439) | 127.91±19.22 (860) | 128.14±18.13 (860) | 128.33±18.24 (859) | 129.37±19.56 (860) | 0.39 |
| Median (Q1,Q3) | 126.00 (115.00,139.00) | 125.00 (114.00,138.00) | 126.00 (115.00,138.00) | 126.00 (116.00,140.00) | 127.00 (115.00,140.00) | |
| Range (min,max) | (77.00,236.00) | (77.00,236.00) | (87.00,203.00) | (91.00,212.00) | (85.00,217.00) | |
| Antihypertensive Medication Use | 28.1% (963/3427) | 25.2% (216/858) | 28.6% (245/858) | 29.2% (249/853) | 29.5% (253/858) | 0.17 |
| Diabetes | 9.9% (340/3435) | 5.5% (47/860) | 9.7% (83/859) | 11.1% (95/857) | 13.4% (115/859) | <0.001 |
| Prevalent Cancer | 6.1% (210/3439) | 6.4% (55/860) | 6.2% (53/860) | 5.4% (46/859) | 6.5% (56/860) | 0.75 |
| Prevalent Breast Cancer | 1.4% (49/3439) | 1.6% (14/860) | 1.2% (10/860) | 1.3% (11/859) | 1.6% (14/860) | 0.79 |
SD denotes: standard deviation; BMI denotes: body-mass index; HDL denotes: high density lipoprotein cholesterol; LDL denotes: low density lipoprotein cholesterol; mg/dL denotes: milligrams per deciliter; Q denotes: quartile; mm Hg denotes: millimeter of mercury.