Table 2.
a. Recruitment Source: Mass Mailings
| Randomization Status* | Randomization Yield (%) |
|||
|---|---|---|---|---|
| Category | Screened (N=4829) |
Not Randomized (N=1827) |
Randomized (N=3002) |
|
| Sex | ||||
| Female | 1701 (35.3%) | 854 (46.8%) | 847 (28.2%) | 49.8 |
| Male | 3124 (64.7%) | 969 (53.2%) | 2155 (71.8%) | 69 |
| Race/Ethnicity | . | |||
| African American |
1491 (30.9%) | 654 (35.8%) | 837 (27.9%) | 56.1 |
| Hispanic | 169 (3.5%) |
61 (3.3%) | 108 (3.6%) | 63.9 |
| Other | 120 (2.5%) |
60 (3.3%) | 60 (2.0%) | 50 |
| White | 3048 (63.1%) | 1051 (57.6%) | 1997 (66.5%) | 65.5 |
| CKD Status | . | |||
| eGFR ≥ 60 | 2889 (73.7%) | 710 (77.3%) | 2179 (72.6%) | 75.4 |
| eGFR < 60 (CKD subgroup) |
1031 (26.3%) | 208 (22.7%) | 823 (27.4%) | 79.8 |
| Age | . | |||
| < 75 Years Old | 3098 (64.2%) | 1290 (70.8%) | 1808 (60.2%) | 58.4 |
| ≥ 75 Years Old | 1726 (35.8%) | 532 (29.2%) | 1194 (39.8%) | 69.2 |
| CVD History | . | |||
| None | 3465 (81.5%) | 1068 (85.3%) | 2397 (79.8%) | 69.2 |
| Clinical or Subclinical CVD |
789 (18.5%) | 184 (14.7%) | 605 (20.2%) | 76.7 |
| Framingham Risk Score - % mean |
16.2 ± 3.7 | 13.4 ± 4.0 | 17.8 ± 2.4 | |
| b. Recruitment Source: Media: television, radio, newspaper, internet, toll-free number | ||||
|---|---|---|---|---|
| Randomization Status* | Randomization Yield (%) |
|||
| Category | Screened (N=1244) |
Not Randomized (N=544) |
Randomized (N=700) |
|
| Sex | ||||
| Female | 635 (51.1%) | 319 (58.9%) | 316 (45.1%) | 49.8 |
| Male | 607 (48.9%) | 223 (41.1%) | 384 (54.9%) | 63.3 |
| Race/Ethnicity | . | |||
| African American | 460 (37.0%) | 253 (46.5%) | 207 (29.6%) | 45 |
| Hispanic | 146 (11.7%) | 23 (4.2%) | 123 (17.6%) | 84.2 |
| Other | 25 (2.0%) | 11 (2.0%) | 14 (2.0%) | 56 |
| White | 613 (49.3%) | 257 (47.2%) | 356 (50.9%) | 58.1 |
| CKD Status | . | |||
| eGFR ≥ 60 | 829 (84.8%) | 252 (90.6%) | 577 (82.4%) | 69.6 |
| eGFR < 60 (CKD subgroup) |
149 (15.2%) | 26 (9.4%) | 123 (17.6%) | 82.6 |
| Age | . | |||
| < 75 Years Old | 1041 (83.7%) | 457 (84.0%) | 584 (83.4%) | 56.1 |
| ≥ 75 Years Old | 203 (16.3%) | 87 (16.0%) | 116 (16.6%) | 57.1 |
| CVD History | . | |||
| None | 962 (91.1%) | 337 (94.7%) | 625 (89.3%) | 65 |
| Clinical or Subclinical CVD |
94 (8.9%) | 19 (5.3%) | 75 (10.7%) | 79.8 |
| Framingham Risk Score - % mean |
15.3 ± 3.5 | 12.9 ± 3.7 | 16.9 ± 2.3 | |
| c. Recruitment Source: Brochure or Poster | ||||
|---|---|---|---|---|
| Randomization Status* | Randomization Yield (%) |
|||
| Category | Screened (N=2195) |
Not Randomized (N=879) |
Randomized (N=1316) |
|
| Sex | ||||
| Female | 923 (42.1%) | 452 (51.5%) | 471 (35.8%) | 51 |
| Male | 1271 (57.9%) | 426 (48.5%) | 845 (64.2%) | 66.5 |
| Race/Ethnicity | . | |||
| African American |
728 (33.2%) | 325 (37.1%) | 403 (30.6%) | 55.4 |
| Hispanic | 131 (6.0%) | 26 (3.0%) | 105 (8.0%) | 80.2 |
| Other | 63 (2.9%) | 31 (3.5%) | 32 (2.4%) | 50.8 |
| White | 1271 (58.0%) | 495 (56.4%) | 776 (59.0%) | 61.1 |
| CKD Status | . | |||
| eGFR ≥ 60 | 1415 (79.5%) | 374 (80.8%) | 1041 (79.1%) | 73.6 |
| eGFR < 60 (CKD subgroup) |
364 (20.5%) | 89 (19.2%) | 275 (20.9%) | 75.5 |
| Age | . | |||
| < 75 Years Old | 1584 (72.3%) | 663 (75.7%) | 921 (70.0%) | 58.1 |
| ≥ 75 Years Old | 608 (27.7%) | 213 (24.3%) | 395 (30.0%) | 65 |
| CVD History | . | |||
| None | 1672 (85.7%) | 562 (88.6%) | 1110 (84.3%) | 66.4 |
| Clinical or Subclinical CVD |
278 (14.3%) | 72 (11.4%) | 206 (15.7%) | 74.1 |
| Framingham Risk Score - % mean |
15.7 ± 3.7 | 13.1 ± 3.9 | 17.3 ± 2.4 | |
| d. Recruitment Source: Referral from SPRINT Staff, Healthcare Provider, Friends | ||||
|---|---|---|---|---|
| Randomization Status* | Randomization Yield (%) |
|||
| Category | Screened (N=6555) |
Not Randomized (N=2069) |
Randomized (N=4486) |
|
| Sex | ||||
| Female | 2820 (43.0%) | 1076 (52.0%) | 1744 (38.9%) |
61.8 |
| Male | 3734 (57.0%) | 992 (48.0%) | 2742 (61.1%) |
73.4 |
| Race/Ethnicity | . | |||
| African American | 2302 (35.3%) | 851 (41.7%) | 1451 (32.3%) |
63 |
| Hispanic | 807 (12.4%) | 131 (6.4%) | 676 (15.1%) | 83.8 |
| Other | 122 (1.9%) | 58 (2.8%) | 64 (1.4%) | 52.5 |
| White | 3298 (50.5%) | 1003 (49.1%) | 2295 (51.2%) |
69.6 |
| CKD Status | . | |||
| eGFR ≥ 60 | 3968 (68.2%) | 952 (71.4%) | 3016 (67.2%) |
76 |
| eGFR < 60 (CKD subgroup) |
1851 (31.8%) | 381 (28.6%) | 1470 (32.8%) |
79.4 |
| Age | . | |||
| < 75 Years Old | 5145 (78.6%) | 1695 (82.2%) | 3450 (76.9%) |
67.1 |
| ≥ 75 Years Old | 1402 (21.4%) | 366 (17.8%) | 1036 (23.1%) |
73.9 |
| CVD History | . | |||
| None | 4699 (78.0%) | 1248 (81.0%) | 3451 (76.9%) |
73.4 |
| Clinical or Subclinical CVD |
1327 (22.0%) | 292 (19.0%) | 1035 (23.1%) |
78 |
| Framingham Risk Score - % mean |
16.2 ± 3.5 | 13.7 ± 4.1 | 17.3 ± 2.6 | |
*
p-value for difference in randomization status between groups ≤ 0.001 for all categories except CKD (p-value=0.0004)
*
p-value for difference in randomization status between groups ≤ 0.001 for all categories except age (p=0.78)
*
p-value for difference in randomization status between groups ≤ 0.001 for all categories except age (p=0.004) and CVD (p=0.011)
*
p-value for difference in randomization status between groups ≤ 0.001 for all categories except CKD (p=0.004)