Table 2.
Culture, pan-Aspergillus PCR, and CYP51A PCR detection in different patient groups.
| Clinical diagnosis | Culture | pan-Aspergillus PCR | CYP51A PCR | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Aspergillus spp.a | Non-Aspergillus spp. | neg. | Total (%)e | Pos. | Neg. | Total (%) | Pos. | Neg. | Total (%) | |
| ABPA | 5 | 1b | 2 | 8 (62.5) | 6 | 2 | 8 (75) | 6 | 2 | 8 (75) |
| CPA | 3 | 0 | 1 | 4 (75) | 4 | 0 | 4 (100) | 4 | 0 | 4 (100) |
| IA | 9 | 0 | 12 | 21 (42.9) | 19 | 2 | 21 (90.5)f | 16 | 5 | 21 (76.2) |
| Colonization | 3 | 1c | 15 | 19 (15.8) | 14 | 5 | 19 (73.7)f | 12 | 7 | 19 (63.2) |
| Control | 0 | 2d | 43 | 45 | 1 | 44 | 45 (2.2) | 0 | 45 | 45 |
| Total | 20 | 4 | 73 | 97 | 44 | 53 | 97 | 38 | 59 | 97 |
a
Except one isolate from an IA patient is A. flavus, all isolates are A. fumigatus.
b
Scedosporium spp.
c
Penicillium spp.
d
Non-Aspergillus spp. include 1 Exophiala spp., and 1 Penicillium spp.
e
% is Aspergillus spp. culture positivity.
f
PCR detection positivity significantly higher than culture, P = 0.0025 for IA group, and P = 0.0008 for colonization group.