Fig. 1.

A: GC content and the position of coding sequences (CDSs) for genes related to equol (EQL) metabolism in Eggerthella sp. YY7918. The horizontal lines indicate a GC content of 71.2%, 56.2% (the GC content of the whole genome sequence), and 41.2%. The coding regions for daidzein reductase (DZNR), dihydrodaidzein reductase (DHDR), and tetrahydrodaidzein reductase (THDR) commenced at nucleotides 15730, 15750, and 15760, respectively. The eqlA, eqlB, and eqlC genes (all in black) were amplified by polymerase chain reaction using the oligonucleotide primers described in Table 1. B: The metabolic pathway for the conversion of daidzein (DZN) to S-EQL by Eggerthella sp. strain YY7918.