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. 2016 Jul 11;8(2):179–184. doi: 10.1159/000446836

Table 1.

Diagnostic criteria for AD

American Academy of Dermatology [13] Hanifin's and Rajka's criteria [14]
Essential features (must be present) Major criteria (must have 3)
 Pruritus Pruritus
 Eczema (acute, subacute, chronic) Dermatitis affecting flexural surfaces in adults or face and extensor surfaces in infants
  Typical morphology and age-specific patternsa Chronic or relapsing dermatitis
  Chronic or relapsing history Personal or family history of cutaneous or respiratory allergy
Important features Minor criteria (must have 3)
 Early age of onset Facial features (infraorbital darkening, etc.)
 Atopy Triggers (environmental factors, etc.)
  Personal and/or family history Complications (susceptibility to skin infections, etc.)
  IgE reactivity Other (early age of onset, dry skin, etc.)
 Xerosis
a

Patterns include: facial, neck, and extensor involvement in infants and children; current or prior flexural lesions in any age group, and sparing of groin and axillary regions.