Table 2.
Baseline characteristics and mean adipokine levels and FLI in incident cases of dementia and subjects without dementia at the end of follow-up
| Demented (n = 42) | Nondemented (n = 625) | p | |
|---|---|---|---|
| Agea, years | 67.4± 0.49 (65.66–69.09) | 65.88± 3.02 (65.64–66.11) | 0.0037 |
| Gender | n.s. | ||
| Women | 64.3 (48.0–78.4) | 70.4 (66.7–74.1) | |
| Men | 35.7 (21.6–52.0) | 29.6 (25.9–33.3) | |
| Years of education | 0.002 | ||
| 0–7 | 83.3 (70.9–95.8) | 59.3 (55.3–63.2) | |
| ≥8 | 16.7 (4.2–29.1) | 40.7 (36.8–44.7) | |
| Leptin, ng/ml | 22.57± 15.71 (21.33–23.80) | 20.76± 16.16 (15.73–25.80) | 0.472b |
| sOB-R, ng/ml | 44.94± 23.97 (37.47–52.41) | 33.73± 21.13 (32.07–35.39) | 0.0012b |
| FLI | 0.013a | ||
| Mean ± SD | 0.69± 0.86 (0.42–0.96) | 0.88± 0.85 (0.81–0.95) | |
| Median (25th-75th percentile) | 0.33 (0.17–0.84) | 0.63 (0.17–0.84) | |
| Adiponectin, ng/ml | 13.44± 4.91 (11.90–14.99) | 11.68± 5.163884 (11.24–12.12) | 0.035b |
| BMI | 0.012 | ||
| <20 | 7.14 (1.49–19.48) | 1.12 (0.45–2.3) | 0.0144 |
| 20–24.9 | 21.43 (10.3–36.8) | 17.34 (14.4–20.5) | 0.64 |
| 25–29.9 | 35.71 (21.55–51.97) | 47.19 43.20–51.20) | 0.199 |
| >30 | 35.71 (21.55–51.97) | 34.35 (30.6–38.2) | 0.99 |
| Waist circumference (>88 cm in men, >102 cm in women) | 54.8 (38.5–71.0) | 60.2 (56.2–64.1) | 0.492 |
| Diabetes | 16.7 (6.97–31.36) | 16.5 (13.46–19.50) | n.s. |
| Depression | 69.2 (48.2–85.7) | 28.1 (24.3–32.0) | <0.001 |
| Hypertension | 56.4 (39.6–72) | 45.9 (41.9–49.9) | n.s. |
Values are means ± SD with 95% CI in parentheses or percentages with 95% CI in parentheses, unless indicated otherwise.
a
Mann-Whitney test.
b
t test.