Structural comparison between the Lethocerus Tn complex and vertebrate x-ray structures.
A, structural superposition of the template structure of the skeletal Tn trimer 1YTZ (blue) and the Lethocerus model (orange). B–D, superposition of the individual chains TnC (B), TnH/TnI (C), and TnT (D). Large insertions modeled by iterative gap growing are shown in green. E, mapping of the TnH peptides (purple) onto the trimer structure, showing their interactions with TnC.