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Influence of GdmCl on the indole side chain (A) and backbone amide (B) resonances of the four tryptophan residues of holoBcII. The combined CSPs for side chain Hϵ1-Nϵ1 (A) and backbone H-N peaks (B) are plotted as a function of GdmCl concentration. The solvent accessibility of the corresponding side and main chains, as computed with NACCESS (59), is indicated.
