Table 1. Corneal erosion grading after 7 days of topical eye drops treatment.

Values are presented as mean ± standard deviation.

After 10 days of dry eye (DE) induction, topical eye drops were given to the mice and corneal fluorescein staining was examined with a slit lamp biomicroscope on treatment day 7. Groups were divided as follows: normal, DE induced, DE + vehicle, DE + HL036337 0.25 mg/mL, DE + HL036337 0.5 mg/mL, DE + HL036337 1 mg/mL, DE + HL036337 2.5 mg/mL, DE + HL036337 5 mg/mL, and DE + Restasis. Punctate staining was evaluated in a masked fashion using the Oxford Scheme grading system, where a grade of 0 to 4 was given for each cornea. Each experiment was repeated three times (p < 0.05).