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The Effect of Inflammatory Bowel Disease Treatment on Fertility in Men and Women
| Inflammatory Bowel Disease Treatment | Effect on Fertility | |
|---|---|---|
| Men | Women | |
| Sulfasalazine | Reduces | Has no effect |
| 5-aminosalicylic acid | Has no effect | |
| Methotrexate | Reduces | N/A (teratogenic) |
| Corticosteroids | Reduces | Has no effect |
| 6-mercaptopurine/azathioprine | Has no effect | |
| Biologic agents | Unknown (but unlikely) | |
| Ileal pouch-anal anastomosis | Reduces | |
Adapted from Heetun ZS et al.31
