Table 2. An alphabetical list of dysregulation of genes and signaling pathways seen in the cutaneous T cell lymphomas.

AT-rich interactive domain-containing protein 1A (ARID1A) 23 B-Raf proto-oncogene, serine/threonine kinase (BRAF) 24 Bromodomain-9 (BRD-9) 24 Cancer testis (CT) 2 Caspase recruitment domain (CARD11) 23, 24 C-C chemokine receptor-4 (CCR-4) 23 Chromodomain-helicase-DNA-binding protein (CHD)-3 24 CREB-binding protein (CREBBP) 24 Cyclin-dependent kinase-2 (CDKN-2) 23– 26 Cyclooxygenase-2 (COX-2) 25 Dynamin-3 (DNM-3) 22 Embryonic stem cell regulators 3, 25 Eph receptor A4 (EPHA4) 13 Forkhead box P3 (FOXP3) 27 GATA-binding protein-3 (GATA-3) 22, 25 Histone deacetylase-6 (HDAC-6) 25 Histone-lysine N-methyltransferase (KMT)-2D or myeloid/lymphoid or mixed-lineage leukemia protein-2 (MLL-2) 24 Interleukin-2 receptor common gamma chain (IL-2Rgc) 3, 25 Janus kinase-3 (Jak-3)/signal transducers and activators of transcription (STAT) 25, 28 KIRD3DL2 22 Lysine (K)-specific methyltransferase (KMT)-2C or myeloid/lymphoid or mixed-lineage leukemia protein-3 (MLL-3) 24 MYC-associated factor X (MAX) 25 Metallothioneins I and II (MTI/II) 29 Methylthioadenosine-phosphorylase (MTAP) 30 Mitogen-activated protein kinase 1 (MAPK1) 24 MYC-binding protein (MYCBP) 25 NOTCH1 13, 31 Nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) 3, 24, 25 Nuclear factor of activated T cells (NFAT) 24 Phospholipase C gamma 1 (PLCG1) 23, 32 P21 33 P53 28, 32 Phosphatase and tensin homolog (PTEN) 24, 25, 34 Plastin-3 (PLS-3) 22 Protein kinase, CGMP-dependent (PRKG1) 24 Receptor tyrosine kinase (RTK) 13 Retinoblastoma-1 (RB-1) 24 Ribosomal protein S6 kinase-1 (RPS6KA-1) 23 Runt-related transcription factor-3 (RUNX-3) 22 Src homology region 2 domain-containing phosphatase-1 (SHP1) 25 Special AT-rich sequence-binding protein 1 (SATB1) 29 SRC proto-oncogene, non-receptor tyrosine kinase (Src kinases) 25 Suppressors of cytokine signaling-3 (SOCS3) 25 SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin-A4 (SMARC-A4) 24 Tet methylcytosine dioxygenase 2 (TET2) 24 Thymocyte selection-associated high-mobility group box (TOX) 22, 25 Tumor protein p53 (TP53) 23, 24 Tumor necrosis factor receptor superfamily-1B (TNFRSF-1B) 30 Twist 22 Zinc finger E-box-binding homeobox 1 (ZEB1) 23