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. 2016 Jul 29;6:30484. doi: 10.1038/srep30484

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Different expression levels of Fgf21 in the liver induced by the dietary interventions and age. (b) Significant positive correlation between plasma Fgf21 and Fgf21 expression in the liver. The association between plasma and expression levels of Fgf21 was also compared in other tissue types, (c) epidydimal white adipose tissue (eWAT), (d) muscle, and (e) colon tissue. r values were calculated with Pearson’s correlations and their significance are indicated in the parentheses.