Figure 6. Hepa 1–6-induced HCC development is unaltered in Ly49E KO mice.
(A) Weight of the left large liver lobe 7 days following orthotopic inoculation of Hepa1–6 cells. (B) Leukocyte subpopulations in tumour-free liver tissue (liver) and in tumour-infiltrating cells (tumour) were analysed and compared in WT versus Ly49E KO mice, as indicated. Data are presented as the percentage of the indicated leukocyte subpopulations relative to the total CD45+ leukocyte population. Data shown are from one experiment (WT: n = 3; Ly49E KO: n = 3) and are presented as mean ± s.e.m. Statistical analysis was performed using the non-parametric 2-tailed Mann-Whitney test. When P ≤ 0.05, the P value is indicated. Only significant statistical differences between WT and Ly49E KO are shown.