Table 2. Liver function parameters (bilirubin, Alb, AST, ALT, PT and INR) pre-LTx and 3 months post-LTx.
| Liver | Pre-LTx |
3 months post-LTx |
p-value | Normal range | ||||
|---|---|---|---|---|---|---|---|---|
| parameter | Median | s.d. | Range (min–max) | Median | s.d. | Range (min–max) | ||
| Bilirubin (mg dL−1) | 3.0 | 9.8 | 0.3–46.6 | 0.60 | 0.86 | 0.2–4.1 | 0.000 | 0.2–1.1 |
| Alb (g L−1) | 34.0 | 7.8 | 22–49 | 37.0 | 8.4 | 19–44 | > 0.05 | 34–48 |
| AST (U L−1) | 48 | 36 | 19–153 | 25 | 35 | 8–169 | 0.001 | 0–37 |
| ALT (U L−1) | 31 | 39 | 8–182 | 23 | 56 | 6–283 | > 0.05 | 7–40 |
| PT (%) | 60 | 25 | 21–117 | 88 | 14 | 54–114 | 0.000 | 70–120 |
| INR | 1.43 | 0.72 | 0.9–3.7 | 1.10 | 0.12 | 0.9–1.5 | 0.000 | 0.9–1.1 |
The median, standard deviation and range (minimum value and maximum value observed) are represented for each cohort (pre-LTx and post-LTx). A significant change, i.e. normalization, in bilirubin, AST, PT and INR was observed 3 months post-LTX (p < 0.01, related samples Wilcoxon signed rank test). For clarity, also the normal ranges of these liver function parameters are shown.