Table 2. Mean (SEM) number of days to reach initial MAD stability, response latencies, and saccharin phenotype scores for groups responding under delay discounting schedules for cocaine.
| N | Days to MAD Stability | 0.2 vs. 0.6 mg/kg Cocaine | 0.4 vs. 1.2 mg/kg Cocaine | 0.8 vs. 2.4 mg/kg Cocaine | Saccharin Phenotype Score | ||||
|---|---|---|---|---|---|---|---|---|---|
| Left Response Latency (sec) | Right Response Latency (sec) | Left Response Latency (sec) | Right Response Latency (sec) | Left Response Latency (sec) | Right Response Latency (sec) | ||||
| HiSF | 12 | 23.7(4.3) | 288.5(51.8) | 217.7(20.2) | 125.4(22.4) | 108.2(13.7) | 393.0(38.8) | 352.2(23.4)a | 23.5(3.6) |
| LoSF | 12 | 13.8(1.5)c | 315.9(36.9) | 228.1(35.4) | 236.1(81.5) | 142.2(19.6) | 801.4(386.2) | 471.6(85.9) | 9.6(2.7)c |
| HiSM | 11 | 13.7(2.1)b | 331.4(65.0) | 255.1(61.3) | 119.3(21.1) | 134.7(31.4) | 415.3(90.4) | 406.6(94.0)a | 12.8(2.9)b |
| LoSM | 12 | 10.5(1.8)b,c | 339.8(39.7) | 298.1(80.5) | 300.9(146.2) | 454.8(199.2) | 527.6(117.0) | 304.3(81.7)a | 4.0(1.2)b,c |
a
significantly greater than the 0.2 vs. 0.6 mg/kg cocaine condition
b
significantly less than HiS and LoS females
c
significantly less than HiS males and females