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. 2016 Jul 28;15:130. doi: 10.1186/s12934-016-0527-2

Fig. 3.

Fig. 3

Controlled batch cultivation of itaconic acid producing A. niger transformants. Controlled batch cultivation of AB1.13 strains carrying the full IA biosynthesis cluster. a HPLC analysis of organic acid production during controlled batch cultivations of AB1.13 strains #08, #49 and #63. The highest IA titer is achieved by AB1.13 #49 (11.74 g/L). AB1.13 #08 produces the most CA (21.99 g/L) from all three strains and achieves the lowest IA titer (2.48 g/L). AB1.13 #63 produces 9.52 g/L IA and 18.03 g/L CA. b Biomass development and glucose consumption during controlled batch cultivations of strains #08, #49 and #63