Fig. 1.

Genes selected from the gluconeogenesis, pentose phosphate and shikimate pathway to increase the phenazine yield. DHAP, dihydroxyacetone phosphate; Gly3P, Glycerol 3-phosphate; G6P, glucose 6-phosphate; F16BP, fructose 1,6-bisphosphate; GAP, glyceraldehyde 3-phosphate; F6P, fructose 6-phosphate; 6PGNL, 6-phosphogluconolactone; R5P, ribose 5-phosphate; Ru5P, ribulose 5-phosphate; S7P, sedoheptulose 7-phosphate; Xu5P, xylulose 5-phosphate; PEP, phosphoenolpyruvate; E4P, erythrose 4-phosphate; ACoA, acetyl-coenzyme A; PYR, pyruvate; OAA, oxaloacetate; CIT, citrate; DHQ, 3-dehydroquinic acid; DAHP, 3-deoxy-Darabinoheptulosonate7-phosphate; QA, quinic acid; DHS, 3-dehydroshikimic acid; SA, shikimic acid; GA, gallic acid; PCA, phenazine-1-carboxylic acid; CHO, chorismate; 2-OH-PCA 2-hydroxy-phenazine-1-carboxylic acid. Gene coding for enzymes not named in the figure: pgi phosphoglucose isomerase; glk glucokinase; eno enolase; gapA glyceraldehyde 3-phosphate dehydrogenase; glpK glycerol kinase; glpF glycerol facilitator; fda fructose-1,6-diphosphate aldolase; glpD glycerol-3-P dehydrogenase; fbp fructose 1,6-bisphosphatase; tpiA triosephosphate isomerase; talB transaldolase; zwf G6P dehydrogenase; pck PEP carboxykinase; ppc PEP carboxylase; pgm phosphoglyceromutase; pgk phosphoglycerate kinase