Table 1.
Demographic and Clinical Characteristics in 1,042 Patients With Melanoma
Characteristic | Data Set (N = 1,042) |
---|---|
Age at blood draw, years | |
Median | 54.8 |
Interquartile range | 44.2-66.0 |
No. (%) female | 452 (43.4) |
Tumor thickness, mm | |
Median | 1.2 |
Interquartile range | 0.7-2.4 |
No./No. evaluated (%) with ulceration | 176/840 (21.0) |
No./No. evaluated (%) with ≥ 1 mitosis per mm2 | 455/654 (69.6) |
No. (%) with SLN biopsy performed | 695 (66.7) |
No./No. with biopsy performed (%) with positive SLN | 135/695 (19.4) |
No. (%) with stage III/IV at blood draw, | 349 (33.5) |
No. (%) by spring/summer season | 515 (49.4) |
Time from diagnosis to blood draw, years | |
Median | 0.6 |
Interquartile range | 0.1-2.4 |
Storage time from blood draw to Vitamin D testing, years | |
Median | 5.1 |
Interquartile range | 3.7-6.7 |
Vitamin D level, ng/mL | |
Median | 25.0 |
Interquartile range | 20.1-30.6 |
No. (%) with vitamin D < 20 ng/mL | 256 (24.6) |
No. (%) with vitamin D ≥ 20 and < 30 ng/mL | 497 (47.7) |
No. (%) with vitamin D ≥ 30 ng/mL | 289 (27.7) |
CRP, mg/L | |
Median | 1.7 |
Interquartile range | 0.7-4.4 |
Follow-up time from blood draw to disease relapse or censoring, years | |
Median | 7.2 |
Interquartile range | 4.4-9.1 |
Follow-up time from blood draw to death or censoring, years | |
Median | 7.1 |
Interquartile range | 3.8-9.0 |
No./No. evaluated (%) with recurrence among all patients | 148/881(16.8) |
No./No. evaluated (%) with recurrence among patients with stage I/II disease | 71/692 (10.3) |
No. (%) of deaths | 294 (28.2) |
No. (%) of deaths as a result of melanoma | 191 (18.3) |
Abbreviations: CRP, C-reactive protein; SLN, sentinel lymph node.