Table 1.
Basic Demographic, Clinical, Treatment, and Psychiatric Outcomes, Compared by Receipt of ADT
| Characteristic | No ADT | ADT | |||
|---|---|---|---|---|---|
| No. of Patients | % | No. of Patients | % | P | |
| Age, years | < .001 | ||||
| Median | 72.6 | 75.2 | |||
| IQR | 69.2-76.7 | 71.3-79.4 | |||
| Mean | 73.5 | 75.7 | |||
| Race | < .001 | ||||
| White | 37,781 | 84.6 | 28,015 | 82.7 | |
| Black | 4,471 | 10.0 | 3,532 | 10.4 | |
| Other | 2,418 | 5.0 | 2,335 | 7.0 | |
| Risk group | < .001 | ||||
| A | 29,839 | 66.8 | 17,202 | 50.8 | |
| B | 9,489 | 21.2 | 13,800 | 40.7 | |
| C | 5,342 | 12.0 | 2,880 | 8.5 | |
| CCI | < .001 | ||||
| 0 | 29,546 | 66.1 | 21,814 | 64.4 | |
| 1 | 11,678 | 26.2 | 8,266 | 24.4 | |
| 2 | 3,446 | 7.7 | 3,802 | 11.2 | |
| Primary treatment | < .001 | ||||
| ADT | 0 | 0.0 | 9,849 | 29.1 | |
| Prostatectomy | 11,324 | 25.3 | 2,048 | 6.0 | |
| RT or BT | 19,736 | 44.2 | 21,985 | 64.9 | |
| Observation | 13,610 | 30.5 | 0 | 0.0 | |
| ADT in first 2 years, months | < .001 | ||||
| None | 44,670 | 100.0 | 0 | 0.0 | |
| 1-6 | 0 | 0.0 | 15,350 | 45.3 | |
| 7-11 | 0 | 0.0 | 7,474 | 22.1 | |
| ≥12 | 0 | 0.0 | 11,058 | 32.6 | |
| Depression after t0 | < .001 | ||||
| No | 42,369 | 94.9 | 31,495 | 93.0 | |
| Yes | 2,301 | 5.2 | 2,387 | 7.1 | |
| Inpatient psychiatric treatment after t0 | < .001 | ||||
| No | 43,826 | 98.1 | 32,923 | 97.2 | |
| Yes | 844 | 1.9 | 959 | 2.8 | |
| Outpatient psychiatric treatment after t0 | < .001 | ||||
| No | 43,536 | 97.5 | 32,746 | 96.7 | |
| Yes | 1,134 | 2.5 | 1,136 | 3.4 | |
Abbreviations: ADT, androgen deprivation therapy; BT, brachytherapy; CCI, Charlson comorbidity index; IQR, interquartile range; RT, radiation therapy; t0, time 0 (defined as 6 months after diagnosis).