Table A2.
Demographics, Smoking Exposure, and Clinical Characteristics of Patients With OPC by Known and Unknown HPV Status
| Characteristic | No. (%) of Patients by HPV Status | P | |
|---|---|---|---|
| Known (n = 748) | Unknown (n = 789) | ||
| Age, years | |||
| Mean (SD) | 57.4 (9.0) | 57.7 (9.9) | .568* |
| Median (IQR) | 56.5 (52-63) | 57 (51-64) | .720 |
| Sex | .475 | ||
| Male | 640 (85.6) | 685 (86.8) | |
| Female | 108 (14.4) | 104 (13.2) | |
| Smoking status | .013 | ||
| Never | 357 (47.7) | 321 (40.7) | |
| Former | 246 (32.9) | 279 (35.4) | |
| Current | 145 (19.4) | 189 (24.0) | |
| T category | .001 | ||
| T1 | 236 (31.6) | 198 (25.1) | |
| T2 | 269 (36.0) | 275 (34.9) | |
| T3 | 142 (19.0) | 159 (20.2) | |
| T4 | 101 (13.5) | 157 (19.9) | |
| N category† | .002 | ||
| N0 | 55 (7.4) | 95 (12.1) | |
| N1 | 90 (12.1) | 111 (14.1) | |
| N2a | 71 (9.5) | 72 (9.1) | |
| N2b | 332 (44.4) | 284 (36.0) | |
| N2c | 156 (20.9) | 166 (21.1) | |
| N3 | 43 (5.8) | 60 (7.6) | |
Abbreviations: HPV, human papillomavirus; IQR, interquartile range; NPC, nasopharyngeal cancer; OPC, oropharyngeal cancer; SD, standard deviation.
*
Adjusted for unequal variances.
†
N category could not be determined in two patients (n = 1 with known and n = 1 with unknown HPV status).