Table 2.
Multivariable Analysis of Factors Associated With OS in HLA-Matched Training Cohort
| Factor | No. of Patients | HR for Death (95% CI) | P |
|---|---|---|---|
| Patient age, years | .003 | ||
| 18-29 | 77 | 1 (reference) | |
| 30-49 | 289 | 1.60 (1.09 to 2.35) | |
| ≥ 50 | 785 | 1.93 (1.36 to 2.83) | |
| KPS, % | .014 | ||
| 90-100 | 702 | 1 (reference) | |
| < 90 | 386 | 1.25 (1.06 to 1.28) | |
| Cytogenetics | < .001 | ||
| Very good, good, or intermediate | 720 | 1 (reference) | |
| Poor or very poor | 149 | 1.43 (1.14 to 1.80) | |
| MK | 195 | 2.01 (1.65 to 2.45) | |
| Blood blast before HCT, % | .005 | ||
| ≤ 3 | 877 | 1 (reference) | |
| > 3 | 89 | 1.41 (1.08-1.85) | |
| Platelet count before HCT, × 109/L | < .001 | ||
| > 50 | 658 | 1 (reference) | |
| ≤ 50 | 489 | 1.37 (1.18 to 1.61) |
Abbreviations: HCT, hematopoietic cell transplantation; HR, hazard ratio; KPS, Karnofsky performance status; OS, overall survival.