Table 4.
Relapse, TRM, and DFS in Combined HLA-Matched Training and Validation Cohorts by Prognostic Score
| Risk Score | No. of Patients | Relapse | TRM | DFS | |||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | ||
| Low | 139 | 1.00 | 1.00 | 1.00 | |||
| Intermediate | 696 | 2.09 (1.3 to 3.36) | .002 | 1.40 (0.99 to 1.97) | .0582 | 1.63 (1.23 to 2.15) | < .001 |
| High | 332 | 3.71 (2.28 to 6.04) | < .001 | 1.92 (1.33 to 2.79) | < .001 | 2.53 (1.89 to 3.39) | < .001 |
| Very high | 60 | 7.49 (4.11 to 13.66) | < .001 | 4.43 (2.71 to 7.27) | < .001 | 5.47 (3.75 to 7.98) | < .001 |
| Overall P | < .001 | < .001 | < .001 | ||||
Abbreviations: DFS, disease-free survival; HR, hazard ratio; TRM, treatment-related mortality.