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. 2015 Sep 1;7(6):1195–1204. doi: 10.1080/19420862.2015.1086854

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© 2015 The Author(s). Published with license by Taylor & Francis

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 4. — Pharmacokinetic analysis of single-dose TTAC-0001 treatment. Profile of serum TTAC-0001 concentration vs. time in mice given an intravenously administered single dose of TTAC-0001. At the indicated times after dosing, serum samples were obtained from caudal vena cava of individual mice, and the concentration of inhibitor in each sample was determined by enzyme-linked immunosorbent assay. These tests were performed in (A) BALB/c mice and (B) BALB/c-nu mice. Mean ± SE.