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. 2016 Jul 25;11:3371–3383. doi: 10.2147/IJN.S108636

Figure 7.

Figure 7

Effect of O-CdTe QDs on cell quantity and autophagy was partially recovered by rapamycin.

Notes: (A) Rapamycin (1 ng/mL) reduced the toxicity of O-CdTe QDs at 8 hours. Toxicity was determined by colony-forming units (CFU). The results are expressed as mean ± standard deviation, n=3. *P<0.05. (B) Rapamycin partially recovered the transformation from GFP-Atg8 to GFP, which was inhibited by O-CdTe QDs at 16 hours. Intracellular GFP-Atg8 and GFP were measured using antibodies to GFP. (C) Quantification of (B). The ratio of free GFP/GFP-Atg8 in each group was calculated. The results are expressed as mean ± standard deviation, n=3. **P<0.01.

Abbreviations: CdTe QDs, cadmium telluride quantum dots; O-CdTe, orange-emitting CdTe; Rap, rapamycin.