Table 4.
Patents and patent applications related to B7 ligands naming Dr. Lieping Chen as inventor
| Patent | Priority date | Assignee | Inventor | claimed subject matter |
|---|---|---|---|---|
| US8460927 | Nov 30, 1999 | Mayo Clin | Chen | 1. method for inhibiting a co-stimulatory effect of B7-H1 on T-cells by administration of an anti-B7-H1 antibody 2. antibody that binds specifically to B7-H1 |
| US6803192 | Nov 30, 1999 | Mayo Clin | Chen | Sequence of B7-H1 |
| US9062112 | Nov 30, 1999 | Mayo Clin | Chen | Sequence of B7-H |
| US8981063 | Nov 30, 1999 | Mayo Clin | Chen | antibody that binds specifically to B7-H1 |
| US7432351 | Oct 4, 2002 | Mayo Clin | Chen | mutant of B7-H1 |
| US8039589 | Oct 4, 2002 | Mayo Clin | Chen | Sequence of a variant of wild-type B7-DC |
| US8273864 | Oct 4, 2002 | Mayo Clin | Chen | Sequence of a variant of wild-type B7-DC (=PD-L2) |
| US7449300 | Nov 21, 2002 | Mayo Clin | Chen | A method of diagnosing an autoimmune disease by testing a sample for antibodies that bind to wild-type B7-H1 |
| US8747833 | Oct 6, 2004 | Mayo Clin | Chen | method for immunotherapy treatment of renal cell carcinoma with interleukin-2, comprising tesing cells for expression of B7-H1 |
| US7892540 | Oct 6, 2004 | Mayo Clin | Chen | method for treating cancer by administering an antibody that blocks B7-H1 interactions with PD-1, e.g., an anti-B7-H1 antibody, wherein cancer cells or tumor-infiltrating leukocytes express B7-H1 |
| US20090304711* | Sept 20, 2006 | Mayo Clin | Chen et al | method of enhancing efficacy of a vaccine by administering an agent that blocks B7-H1 interactions with PD-1, e.g, an anti-B7-H1 antibody |
*
pending.