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. Author manuscript; available in PMC: 2016 Jul 29.
Published in final edited form as: Prog Mol Biol Transl Sci. 2014;123:143–167. doi: 10.1016/B978-0-12-397897-4.00002-4

Figure 7.1.

Figure 7.1

Differential geometry approach for interfacing the membrane with the cytoskeleton. A differential geometry approach is used to represent the membrane and its interaction with the actin filament. Each vertex on the triangulated surface represents an end of one actin filament. The vertices move according to the underlying growth of actin filaments in response to biochemical reactions modulated by the energy penalty imposed by membrane bending and surface resistance. As these events proceed in space and time, we are able to simulate cell spreading behavior.