Figure 1.
Projection of the SCMatom,i values on the Fv domain. (Left) antibody with a low SCM Score, Rituximab (right) antibody with a high SCM Score, N4. Fv domains are oriented so that the light chain is on the left side and the complementarity-determining regions of the antibodies are visible. Red patches indicate electronegative regions, whereas blue patches indicate electropositive patches.