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. 2015 Sep 23;8(1):43–48. doi: 10.1080/19420862.2015.1099773

Table 3.

Antibody isotype, viscosity and SCM scores for MedImmune antibodies. IgG1κ-YTE has triple mutations in the Fc domain for higher FcRn binding19

mAb Isotype Viscosity [mPa-s] SCM score
M1 IgG1κ 11.1 876
M2 IgG1κ 25.8 2223
M3 IgG1κ 5.4 980
M4 IgG1κ-YTE 14.3 1724
M5 IgG1κ 14.9 1724
M6 IgG1κ 13.2 1589