Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jul 29;35:122. doi: 10.1186/s13046-016-0400-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 8 — Inhibition of SMAD7 expression in PSCs reduces tumor stroma interactions and decrease cancer cell migration. a-b PSCs were transfected with non-targeting siRNA (control) or SMAD7 siRNA (100nM) for 3 days, followed by 2 days incubation in serum free medium and another 3 days of culture in the presence or absence of IL-1α (1 ng/ml) or (c-d) 12 h of indirectly co-culture with 5×10⁵ BxPC-3 cells and additionally 60 h of culture without any supplements. The supernatants were harvested 5 days post siRNA transfection and transferred to BxPC-3 scratch wound assays. Wound recovery was determined after 24 h and the data was normalized to controls. Error bars represent S.E.M.; ***p < 0.001