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. 2016 Jul 29;8:55. doi: 10.1186/s13098-016-0171-3

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Methylation profile and linkage disequilibrium (LD) map within the TOMM20 locus. The upper part of the figure shows mean methylation levels of the 20 CpG (CpG island—grey bars; upstream and downstream regions—black bars) identified within TOMM20 locus in visceral adipose tissue samples (n = 48). Methylation levels shown as average β values ranging from 0 (unmethylated) to 1 (completely methylated). The lower part shows the LD map of genotyped and imputed SNPs within TOMM20 locus in the study population (n = 1720), considering the CEU panel (Utah residents with Northern and Western European ancestry) of the latest release of the 1000 Genomes Project (Phase 3). LD r² values (%) are shown in boxes. The imputed SNP is marked with an asterisk