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. 2016 Jan 29;8(2):253–263. doi: 10.1080/19420862.2015.1128605

Table 1.

Summary of human IGγ1 (G1m) allotypes and their associated genotypes (From: http://www.imgt.org).

G1m allotypes
Amino acid positionsa
CH1 CH3 CH1 CH3
    120 12 14
    (97) (16) (18)
    214 356 358
G1m17 G1m1 Lys Asp Leu
    aAa gaT Ctg
G1m3 nG1m1 Arg Glu Met
    aGa gaG Atg
a

Amino acid numbers (bold) are defined according to IMGT unique numbering for C-DOMAIN36; http://www.imgt.org). Numbers in parentheses define exons. Numbers in italics define Eu numbering. 37 The G1m17 allotype (Lys at position 120; CH1) and G1m1 allotype (Asp and Leu at positions 12 and 14, respectively; CH3) are both found on IGHG1*01 and IGHG1*2 alleles. The G1m3 allotype (Arg at position 120; CH1) and nG1m1 (Glu and Met at positions 12 and 14, respectively) are found on IGHG1*03 allele. Upper case letter within 3 letter amino acid code indicates polymorphic nucleotide.