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. 2015 Dec 14;8(2):306–317. doi: 10.1080/19420862.2015.1116659

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 6. — Evaluation of 2DLC configuration. NAc-linker-DSEA, spiked into a dilute trastuzumab sample, was successfully transferred from (A) the SPE column (1^st dimension) to the (B) RP column (2^nd dimension) using the 2DLC configuration illustrated in Figure 4A as proof-of-principle.