Table 3.
Multiple logistic regression models (unadjusted and adjusted) for dichotomous 55-Item frailty index and for worsening frailty index with three categories of cancer status: without cancer, remote cancer, and recent cancer
| Analysis | Groups | Unadjusted OR (95 % CI) | p value | Adjusted OR (95 % CI)a | p value |
|---|---|---|---|---|---|
| FI > 0.25 in follow-up | Reference versus group 1 | 1 (0.61–1.64) | 0.98 | 0.81 (0.39–1.64) | 0.561 |
| Reference versus group 2 | 1.53 (1.04–2.26) | 0.03 | 1.74 (1.15–2.61) | 0.008 | |
| Group 1 versus group 2 | 0.65 (0.35–1.21) | 0.18 | 0.46 (0.2–1.04) | 0.065 | |
| Worsening of the FI | Reference versus group 1 | 0.56 (0.39–0.8) | 0.002 | 0.61 (0.38–0.99) | 0.046 |
| Reference versus group 2 | 1.12 (0.81–1.54) | 0.463 | 1.03 (0.74–1.43) | 0.838 | |
| Group 1 versus group 2 | 0.5 (0.31–0.8) | 0.004 | 0.59 (0.95–2.96) | 0.074 |
Reference corresponds to the group without cancer
Group 1 corresponds to the group with cancer of more than 10 years since diagnosis
Group 2 corresponds to the group with cancer of 10 years or less since diagnosis
OR odds ratio, CI confidence intervals, FI frailty index
Adjusted for age, sex, marital status, years in school, at least one negative event in the last 11 years, smoking status and cognitive decline, chemotherapy, surgery, and radiotherapy interaction