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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Open Life Sci. 2015 Oct 19;10(1):461–478. doi: 10.1515/biol-2015-0048

Figure 7. Myristoylated-p110α is ubiquitously expressed in all tissues.

Figure 7

(A) Cre;WT embryo at E15.5 in mixed genetic background with normal phenotype. (B) Cre;myr-p110α embryo at E15.5 in mixed genetic background displaying extensive hemorrhaging areas in the embryo. (C) Fluorescence image of WT embryo shown in (A), presenting no GFP signal. (D) Fluorescence image of Cre;myr-p110α embryo shown in (B), revealing significant levels of GFP signal. The fluorescent signals of GFP did not employ enzymatic amplification. Pictures are representative of total 14 embryos analyzed. Bar in panel (A) represents 0.5 cm and indicates scale for (A) to (D).