Table 1.

AMPK activators and research stages in disease treatment.

Type of molecule	Diabetes	Cancer	Cardiovascular Disease
Metformin	Clinical Use [18]	Clinical Research [21] Cell Research [23]	Animal Research [32]
Adiponectin	Animal Research [40]	Cell Research [52]	Animal Research [51]
APC	Clinical Research [57]	Clinical Research [60–62] Cell Research [58,59]	Animal Research [63]
A-769662	Animal Research [66]	Cell Research [67,70]	Animal Research [67]
Salicylate	Clinical Research [81–83]	Cell Research [76,77]	Clinical Use [78]
MIF20	NA	Cell Research [92]	Animal Research [88]
AICAR	Animal Research [96,97]	Clinical Research [94]	Animal Research [95]