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. 2016 Jul 25;9:4583–4591. doi: 10.2147/OTT.S107272

Table 1.

Algorithm genes

Official symbol Name Biological functions Aliases Reference sequence
BAG1 BCL2-associated athanogene Blocks a step in a pathway leading to apoptosis or programmed cell death HAP, BAG-1, RAP46 NM_004323
BRCA1 Breast cancer 1, early onset Induction of apoptosis, protein ubiquitination, regulation of G2/M transition DNA damage checkpoints, regulation of DNA repair IRIS, PSCP, BRCA1, BRCC1, PNCA4, RNF53, BROVCA1, PPP1R53 NM_007294 (672)
CDC6 Cell division cycle 6 homologue Interferes with the expression of INK4/ARF tumor suppressor genes through a mechanism involving the epigenetic modification of chromatin at the INK4/ARF locus CDC18L, HsCDC18, HsCDC6 NM_001254
CDK2AP1 Cyclin-dependent kinase 2 associated protein 1 Regulation of S phase of mitotic cell cycle, epigenetic regulation DOC1, DORC1, ST19, doc-1, p12DOC-1 NM_004642
ERBB3 V-erb-b2 erythroblastic leukemia viral oncogene homologue 3 Encodes a member of the EGFR family of receptor tyrosine kinases, transmembrane receptor protein tyrosine kinase signaling, regulation of phosphoinositide 3-kinase cascade, regulation of cell proliferation ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 NM_001982
FUT3 Fucosyltransferase 3 Carbohydrate metabolism, protein amino acid glycosylation CD174, FT3B, FucT-III, LE, Les NM_000149
IL-11 Interleukin-11 Stimulates T-cell-dependent development of immunoglobulin-producing B cells AGIF, IL-11 NM_000641
LCK Lymphocyte-specific protein tyrosine kinase Regulation of T-cell receptor signaling, leukocyte migration LSK, YT16, IMD22, p56lck, pp58lck NM_001042771
RND3 Rho family GTPase 3 A negative regulator of cytoskeletal organization ARHE, Rho8, RhoE, memB NM_005168
SH3BGR SH3 domain binding glutamic acid-rich protein Protein coding 21-GARP NM_007341

Abbreviations: BCL2, B-cell lymphoma 2; EGFR, epidermal growth factor receptor.