Table 1.
Official symbol | Name | Biological functions | Aliases | Reference sequence |
---|---|---|---|---|
BAG1 | BCL2-associated athanogene | Blocks a step in a pathway leading to apoptosis or programmed cell death | HAP, BAG-1, RAP46 | NM_004323 |
BRCA1 | Breast cancer 1, early onset | Induction of apoptosis, protein ubiquitination, regulation of G2/M transition DNA damage checkpoints, regulation of DNA repair | IRIS, PSCP, BRCA1, BRCC1, PNCA4, RNF53, BROVCA1, PPP1R53 | NM_007294 (672) |
CDC6 | Cell division cycle 6 homologue | Interferes with the expression of INK4/ARF tumor suppressor genes through a mechanism involving the epigenetic modification of chromatin at the INK4/ARF locus | CDC18L, HsCDC18, HsCDC6 | NM_001254 |
CDK2AP1 | Cyclin-dependent kinase 2 associated protein 1 | Regulation of S phase of mitotic cell cycle, epigenetic regulation | DOC1, DORC1, ST19, doc-1, p12DOC-1 | NM_004642 |
ERBB3 | V-erb-b2 erythroblastic leukemia viral oncogene homologue 3 | Encodes a member of the EGFR family of receptor tyrosine kinases, transmembrane receptor protein tyrosine kinase signaling, regulation of phosphoinositide 3-kinase cascade, regulation of cell proliferation | ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 | NM_001982 |
FUT3 | Fucosyltransferase 3 | Carbohydrate metabolism, protein amino acid glycosylation | CD174, FT3B, FucT-III, LE, Les | NM_000149 |
IL-11 | Interleukin-11 | Stimulates T-cell-dependent development of immunoglobulin-producing B cells | AGIF, IL-11 | NM_000641 |
LCK | Lymphocyte-specific protein tyrosine kinase | Regulation of T-cell receptor signaling, leukocyte migration | LSK, YT16, IMD22, p56lck, pp58lck | NM_001042771 |
RND3 | Rho family GTPase 3 | A negative regulator of cytoskeletal organization | ARHE, Rho8, RhoE, memB | NM_005168 |
SH3BGR | SH3 domain binding glutamic acid-rich protein | Protein coding | 21-GARP | NM_007341 |
Abbreviations: BCL2, B-cell lymphoma 2; EGFR, epidermal growth factor receptor.