Table 5.
TNM-based or IASLC/ATS/ERS classification-based models adjusted for risk score and other clinical parameters among the 91 patients with early-stage pulmonary adenocarcinoma
| TNM-based model
|
IASLC/ATS/ERS-based model
|
||||
|---|---|---|---|---|---|
| Variables | Adjusted HR (95% CI) | P-value | Variables | Adjusted HR (95% CI) | P-value |
| RS10 | 3.41 (1.61–7.26) | 0.001* | RS10 | 2.01 (0.93–4.34) | 0.070 |
| TNM stage | 2.72 (1.47–5.05) | 0.001* | IASLC/ATS/ERS | 2.57 (1.60–4.12) | 8.8E-5* |
| Age | 1.41 (0.77–2.57) | 0.270 | Age | 1.14 (0.62–2.10) | 0.690 |
| Sex | 0.54 (0.29–1.02) | 0.053 | Sex | 0.58 (0.31–1.10) | 0.094 |
| Smoking c-index =0.715 | 0.52 (0.24–1.12) | 0.087 | Smoking c-index =0.735 | 0.54 (0.25–1.16) | 0.113 |
Note:
*
P<0.01.
Abbreviations: ATS, American Thoracic Society; CI, confidence interval; ERS, European Respiratory Society; HR, hazard ratio; IASLC, International Association for the Study of Lung Cancer; RS10, risk score of ten-gene signature.