Table 5.

Factors associated with overall survival and disease-free survival on multivariate analyses for group HM + PM

Variable	Overall survival			Disease-free survival
	HR	95 % CI	P value	HR	95 % CI	P value
Age at PM	3.77	1.48–9.59	0.005	1.31	0.68–2.52	0.44
DFI (≥12months)a	0.98	0.95–0.99	0.036	0.98	0.96–0.99	0.003
Multiple LM	3.97	1.53–10.4	0.005	2.0	1.04–3.87	0.039
Size of largest LMb	1.69	1.00–2.83	0.048	1.2	0.89–1.63	0.227

HR hazard ratio, CI confidence interval, PM pulmonary metastasectomy, DFI disease-free interval, LM lung metastases

^aDisease-free interval was calculated as the interval between the date of colorectal cancer resection and the date of pulmonary metastasectomy

^bThe long-axis diameter of the largest lung metastatic nodule was measured