Table 2.
Effect of β-sitosterol upon various in-vivo antioxidant markers
Groups | TBARs (nM of MDA/μg of protein) | GSH (mg %) | SOD (Units of SOD/mg of protein) | Catalase (nM of H2O2/min/mg of protein) |
---|---|---|---|---|
CONTROL (3 ml/kg) | 86.08 ± 5.00*** | 2.30 ± 0.12 | 1.92 ± 0 | 50.63 ± 7.81* |
MNU (47 mg/kg) | 118.84 ± 4.65 | 2.00 ± 0.16 | 1.81 ± 0.02 | 31.76 ± 2.59 |
β-SITOSTEROL + MNU (10 mg/kg + 47 mg/kg) | 147.93 ± 6.67** | 1.03 ± 0.14** | 1.82 ± 0.03 | 26.90 ± 3.06 |
β-SITOSTEROL + MNU (20 mg/kg + 47 mg/kg) | 105.51 ± 2.35 | 1.24 ± 0.21* | 1.80 ± 0.03 | 51.75 ± 3.31* |
(Values are Mean ± SEM), each group contains eight animals. Comparisons were made on the basis of the one-way ANOVA followed by Bonferroni test. All groups were compared to the toxic control group (*p < 0.05, **p < 0.01, ***p < 0.001)