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. 2016 Jul 29;16:561. doi: 10.1186/s12885-016-2592-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Knockdown of HSP70-2 inhibited migration and invasion of CRC cells. a Micrographs depict the reduced migratory and invasive ability of COLO205 post transfection with HSP70-2 shRNA3 and shRNA4 as compare to control NC shRNA. b Representative micrograph shows reduction in migration and invasion of HCT116 cells post transfection with HSP70-2 shRNA3 and shRNA4 compare to control NC shRNA. Histogram shows significant reduction in migration and invasion of COLO205 and HCT116 cells. *p < 0.0001, statistically significant, Original magnification x100, objective x10. All the results are an average of triplicates (n = 3) and the experiments were repeated twice