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Amino acid residues having the most interactions in the models of both subtypes
| Subtype | Protein | Positions | Number of interactions |
|---|---|---|---|
| H1N1 | HA | 222K | 2 |
| M1 | 121T | 5 | |
| M2 | 14G | 6 | |
| NEP | 57S, 60S | 2 | |
| PA | 28P, 277S | 3 | |
| PA-X | 28P | 4 | |
| PB1 | 179M, 741A | 3 | |
| PB2 | 65E | 3 | |
| H3N2 | M1 | 101R | 2 |
| M2 | 11T, 14G, 31S, 54R | 2 | |
| NEP | 14M | 4 | |
| PB1 | 212L | 2 | |
| PB2 | 82N | 6 |
