Table 1.
Reported glycan selectivity of the 45 lectins used in the microarray assay.*16
| Lectin No. | Lectin (origin) | Reported glycan selectivity |
|---|---|---|
| 1 | LTL (Lotus tetragonolobus) | Fucα1-3(Galβ1-4)GlcNAc (Lewis x), Fucα1-2Galβ1-4GlcNAc (H-type 2) |
| 2 | PSA (Pisum sativum) | Fucα1-6GlcNAc (Core Fuc) , α-Man |
| 3 | LCA (Lens culinaris) | Fucα1-6GlcNAc (Core Fuc), α-Man |
| 4 | UEA-I (Ulex europaeus) | Fucα1-2Galβ1-4GlcNAc (H-type 2) |
| 5 | AOL (Aspergillus oryzae) | Fucα1-6GlcNAc (Core Fuc), Fucα1-2Galβ1-4GlcNAc (H-type 2) |
| 6 | AAL (Aleuria aurantia) | Fucα1-3(Galβ1-4)GlcNAc (Lewis x), Fucα1-6GlcNAc (Core Fuc) |
| 7 | MAL_I (Maackia amurensis) | Siaα2-3Galβ1-4GlcNAc |
| 8 | SNA (Sambucus nigra) | Siaα2-6Gal/GalNAc |
| 9 | SSA (Sambucus sieboldiana) | Siaα2-6Gal/GalNAc |
| 10 | TJA-I (Trichosanthes japonica) | Siaα2-6Gal/GalNAc, HSO3(-) -6Galβ1-4GlcNAc |
| 11 | PHAL (Phaseolus vulgaris) | tri/tetra-antennary complex-type N-glycan |
| 12 | ECA (Erythrina cristagalli) | Galβ1-4GlcNAc (up with increasing the number of terminal Gal), no affinity for fully sialylated N-type, fully agalactosylated N-type |
| 13 | RCA120 (Ricinus communis) | Galβ1-4GlcNAc (up with increasing the number of terminal Gal), Galβ1-3Gal (weak), no affinity for agalactosylated N-type |
| 14 | PHAE (Phaseolus vulgaris) | bi-antennary complex-type N-glycan with outer Gal and bisecting GlcNAc, no affinity for fully sialylated N-type |
| 15 | DSA (Datura stramonium) | (GlcNAcβ1-4)n, tri/tetra-antennary N-glycan |
| 16 | GSL-II (Griffonia simplicifolia) | agalactosylated tri/tetra antennary glycans, GlcNAc, no affinity for fully galactosylated or sialylated N-type |
| 17 | NPA (Narcissus pseudonarcissus) | High-Mannose including Manα1-6Man |
| 18 | ConA (Canavalia ensiformis) | High-Mannose including Manα1-6(Manα1-3)Man |
| 19 | GNA (Galanthus nivalis) | High-Mannose including Manα1-3Man |
| 20 | HHL (Hippeastrum hybrid) | High-Mannose including Manα1-3Man or Manα1-6Man |
| 21 | ACG (mushroom, Agrocybe cylindracea) | Galβ1-3Gal, Siaα2-3Galβ1-4GlcNAc |
| 22 | TxLCI (Tulipa gesneriana) | Manα1-3(Manα1-6)Man, bi/tri-antennary complex-type N-glycan, GalNAc |
| 23 | BPL (Bauhinia purpurea) | Galβ1-3GalNAc (up with Lewis x, down with Core Fuc), GalNAc |
| 24 | TJA-II (Tanthes japonica) | Fucα1-2Galβ1-> or GalNAcβ1-> groups at their non-reducing terminals |
| 25 | EEL (Euonymus europaeus) | Galα1-3Galβ1-4GlcNAc, Fucα1-2Galβ1-3GlcNAc (H antigen) |
| 26 | ABA (fungus, Agaricus bisporus) | Galβ1-3GalNAc, GlcNAc |
| 27 | LEL (tomato, Lycopersicon esculentum) | (GlcNAcβ1-4)n (Chitin), (Galβ1-4GlcNAc)n (polylactosamine) |
| 28 | STL (potato, Solanum tuberosum) | (GlcNAcβ1-4)n (Chitin), oligosaccharide containing GlcNAc and MurNAc |
| 29 | UDA (Urtica dioica) | GlcNAcβ1-4GlcNAc (Chitin), High-Mannose (3 to High, up with increasing the number of Man) |
| 30 | PWM (pokeweed, Phytolacca Americana) | (GlcNAcβ1-4)n (Chitin) |
| 31 | Jacalin (Artocarpus integrifolia) | GlcNAcβ1-3GalNAc (Core3), Siaα2-3Galβ1-3GalNAc (sialyl T), Galβ1-3GalNAc (T-antigen), α-GalNAc (Tn-antigen) |
| 32 | PNA (peanut, Arachis hypogaea) | Galβ1-3GalNAc |
| 33 | WFA (Wisteria floribunda) | GalNAcβ1-4GlcNAc (LacdiNAc), Galβ1-3(-6)GalNAc |
| 34 | ACA (Amaranthus caudatus) | Galβ1-3GalNAc (T-antigen), Siaα2-3Galβ1-3GalNAc (sialyl T) |
| 35 | MPA (Maclura pomifera) | α-GalNAc (Tn-antigen), Galβ1-3GalNAc (T-antigen), |
| 36 | HPA (snail, Helix pomatia) | α-GalNAc |
| 37 | VVA (Vicia villosa) | GalNAcβ1-4Gal, GalNAcβ1-3Gal, α-GalNAc |
| 38 | DBA (Dolichos biflorus) | Blood group A, GalNAcα1-3GalNAc, GalNAcβ1-4(Siaα2-3)Galβ1-4Glc (GM2) |
| 39 | SBA (soybean, Dolichos biflorus) | α- or β-linked GalNAc, Galα1-4Gal-Glc |
| 40 | Calsepa (Calystegia sepium) | Galactosylated bianntenary N-type with bisecting GlcNAc (galacto > agalacto, down with Core Fuc), High-Mannose (Man2-6) |
| 41 | PTL-I (Psophocarpus tetragonolobus) | α-GalNAc, Galα1-3(Fucα1-2)Gal (B-antigen) |
| 42 | MAH (Maackia amurensis) | Siaα2-3Galβ1-3(Siaα2-6)GalNAc (disialyl-T) |
| 43 | WGA (wheat germ, Triticum aestivum) | (GlcNAcβ1-4)n (Chitin), Hybrid type N-glycan, Sia |
| 44 | GSL-I A4 (Griffonia simplicifolia) | α-Gal, α-GalNAc |
| 45 | GSL-I B4 (Griffonia simplicifolia) | α-Gal, α-GalNAc |
*
LfDB database http://jcggdb.jp/rcmg/glycodb/LectinSearch