Table 2.
Number | Proprietary name | USAN name | Class | Expression system |
---|---|---|---|---|
1 | Avastin | Bevacizumab | mAb | CHO |
2 | Herceptin | Trastuzumab | mAb | CHO |
3 | Humira | Adalimumab | mAb | CHO |
4 | Remicade | Infliximab | mAb | Sp2/0 |
5 | Rituxan | Rituximab | mAb | CHO |
6 | Xolair | Omalizumab | mAb | CHO |
7 | Vectibix | Panitumumab | mAb | CHO |
8 | Erbitux | Cetuximab | mAb | Sp2/0 |
9 | Enbrel | Etanercept | Fc-fusion protein | CHO |
10 | Aranesp | Darbepoetin alfa | cytokine | CHO |
11 | Pulmozyme | Dornase alfa | enzyme | CHO |
12 | Elitek | Rasburicase | enzyme | S. cerevisiae |
13 | Recombinant human transferrin, expressed in rice | |||
14 | Transferrin purified from human blood plasma | |||
15 | Neupogen | Filgrastim | cytokine | E. coli |
Abbreviations used in this table: mAb, monoclonal antibody; CHO, Chinese Hamster Ovary cells; Sp2/0, murine myeloma cell line; S. cerevisiae, Saccharomyces cerevisiae; E. coli, Escherichia coli.