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. 2016 Mar 16;8(4):811–827. doi: 10.1080/19420862.2016.1160989

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 5. — XGFR* mediated inhibition of A549 and RD-ES cell proliferation. (A) A549 and (B) RD-ES tumor cells were seeded in poly-HEMA coated plates with increasing concentrations of bispecific antibodies XGFR and XGFR* or parental control antibody mixture R1507/GA201 and incubated for 7 d. Cell viability was measured by luminescence after addition of CellTiter Glo reagent. Titration curves in the indicated concentration range and IC50 values are depicted in the table. At least 2 independent data sets with comparable results were obtained.