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Features of aGVHD vs non-aGVHD skin rash in TCD graft recipients
| Histopathologic feature | TCD aGVHD (%) | TCD non-aGVHD (%) |
|---|---|---|
| Diffuse basal vacuolization | 77 | 25 |
| Any single necrotic keratinocyte/HPF | 92 | 45 |
| >3 single necrotic keratinocytes/HPF | 31 | 5 |
| Full thickness necrotic keratinocyte | 42 | 0 |
| Satellitosis | 77 | 30 |
| Exocytosis | 92 | 65 |
| Slight (rather than marked) inflammation | 77 | 20 |
TCD, T-cell depletion, aGVHD, acute graft versus host disease, HPF, high power field
