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Features of aGVHD in TCD vs T replete graft recipients
| Histopathologic feature | TCD aGVHD (%) | T replete aGVHD (%) |
|---|---|---|
| Any necrotic keratinocytes per HPF | 92 | 87 |
| Slight (rather than marked) lymphocytic infiltrate | 77 | 79 |
| Spongiosis | 54 | 55 |
| >3 single necrotic keratinocytes per HPF | 31 | 34 |
| Adnexal involvement | 77 | 16 |
| Satellitosis | 77 | 24 |
| Exocytosis | 92 | 37 |
| Acanthosis | 54 | 8 |
TCD, T-cell depleted, aGVHD, acute graft versus host disease, HPF, high power field
