TABLE 1:

Sequence changes of VPS13 mutant alleles.

VPS13 allele	Nucleotide change	Amino acid change
VPS13	None	None
vps13-31	G 1565∆	Codon 533 stop
VPS13-P268R	C 803 G	Pro 268 Arg
VPS13-G718Ka	G 2152 T	Gly 718 Lys
VPS13-G718Ka	G 2152 T	Gly 718 Lys
VPS13-G718D	G 2153 A	Gly 718 Asp
VPS13-G820R	G 2458 C	Gly 820 Arg
VPS13-G820Db	G 2459 A	Gly 820 Asp
VPS13-L822F c	G 2466 T	Leu 822 Phe
VPS13-L984S	T 2951 C	Leu 984 Ser
VPS13-V1210E	T 3629 A	Val 1210 Glu
VPS13-G1245S	G 3733 A	Gly 1245 Ser
VPS13-N1467H	A 4399 C	Asn 1467 His
VPS13-A1512E	C 4535 A	Ala 1512 Glu

^aMutation was recovered in two independently isolated suppressor strains.

^bOriginally designated YNT61-1 (Hanekamp et. al., 2002).

^cOriginally designated YNT61-3 (Hanekamp et. al., 2002).