Table 3.

Associations between miRNAs differentially expressed between microsatellite stable and microsatellite unstable colon tumors with a false discovery rate set at 0.05

	Microsatellite Stable		Microsatellite Unstable
miRNA	% Expressing	Mean Expression	% Expressing	Mean Expression	Siggenes p value	Fold Change1
hsa-let-7a-5p	99.0	276.83	98.7	183.31	0.000	0.66
hsa-let-7e-5p	94.1	24.07	90.3	15.57	0.000	0.65
hsa-let-7f-5p	98.5	155.97	97.4	96.19	0.000	0.62
hsa-let-7g-5p	97.1	53.66	95.5	34.33	0.000	0.64
hsa-miR-100-5p	70.4	8.80	50.0	4.79	0.000	0.54
hsa-miR-125b-5p	97.3	53.77	96.8	30.40	0.000	0.57
hsa-miR-127-3p	15.0	2.70	5.2	1.15	0.000	0.43
hsa-miR-1291	76.8	5.92	59.1	3.86	0.000	0.65
hsa-miR-130a-3p	49.3	5.88	25.3	2.79	0.000	0.47
hsa-miR-143-3p	63.8	7.07	39.0	2.68	0.000	0.38
hsa-miR-145-5p	99.8	134.19	99.4	77.28	0.000	0.58
hsa-miR-148a-3p	79.4	17.83	60.4	8.17	0.000	0.46
hsa-miR-151a-3p	51.1	4.83	23.4	2.33	0.000	0.48
hsa-miR-151a-5p	91.2	14.36	80.5	6.85	0.000	0.48
hsa-miR-151b	83.5	6.95	66.9	3.51	0.000	0.51
hsa-miR-15a-5p	61.8	6.82	48.1	3.68	0.000	0.54
hsa-miR-17-5p	98.1	53.02	98.1	31.47	0.000	0.59
hsa-miR-183-5p	24.3	4.88	9.7	2.51	0.000	0.51
hsa-miR-185-5p	12.3	3.49	5.8	2.23	0.001	0.64
hsa-miR-1913	14.1	1.93	6.5	0.93	0.001	0.48
hsa-miR-192-3p	21.1	1.58	8.4	0.53	0.000	0.33
hsa-miR-192-5p	97.2	87.65	91.6	50.24	0.000	0.57
hsa-miR-193b-3p	84.6	8.50	64.9	4.59	0.000	0.54
hsa-miR-194-5p	97.3	84.55	92.9	54.19	0.000	0.64
hsa-miR-195-5p	44.1	3.23	20.8	1.12	0.000	0.35
hsa-miR-196a-5p	64.3	6.72	42.2	3.36	0.000	0.50
hsa-miR-196b-5p	81.0	17.51	51.9	4.72	0.000	0.27
hsa-miR-1973	99.8	793.25	100.0	512.18	0.000	0.65
hsa-miR-199a-3p	94.1	38.36	91.6	21.28	0.000	0.55
hsa-miR-199a-5p	89.5	17.08	81.8	8.86	0.000	0.52
hsa-miR-199b-5p	37.9	3.72	12.3	1.62	0.000	0.43
hsa-miR-19b-3p	91.9	25.37	87.7	14.21	0.000	0.56
hsa-miR-200a-3p	93.5	27.08	90.9	17.29	0.000	0.64
hsa-miR-200b-3p	98.4	151.75	98.1	97.72	0.000	0.64
hsa-miR-203a	66.4	11.82	56.5	7.58	0.000	0.64
hsa-miR-204-3p	15.0	1.12	9.7	0.71	0.044	0.64
hsa-miR-20a-5p	97.6	61.83	96.8	33.17	0.000	0.54
hsa-miR-20b-5p	86.7	15.29	79.9	7.72	0.000	0.50
hsa-miR-214-3p	88.7	11.97	81.2	7.47	0.000	0.62
hsa-miR-215	95.6	41.56	89.6	26.31	0.000	0.63
hsa-miR-221-3p	84.6	12.18	70.8	7.46	0.000	0.61
hsa-miR-223-3p	89.5	22.79	94.8	36.61	0.000	1.61
hsa-miR-224-5p	67.6	13.82	17.5	4.55	0.000	0.33
hsa-miR-23a-3p	99.1	157.85	98.7	93.21	0.000	0.59
hsa-miR-23b-3p	98.2	65.43	96.1	35.36	0.000	0.54
hsa-miR-26a-5p	98.7	96.40	98.1	55.09	0.000	0.57
hsa-miR-26b-5p	89.3	18.41	84.4	11.01	0.000	0.60
hsa-miR-27a-3p	97.6	49.86	96.8	30.52	0.000	0.61
hsa-miR-27b-3p	95.5	32.03	92.2	17.97	0.000	0.56
hsa-miR-28-5p	20.7	1.67	5.2	0.42	0.000	0.25
hsa-miR-29a-3p	98.1	97.72	98.1	54.89	0.000	0.56
hsa-miR-29b-3p	93.7	22.49	89.6	13.68	0.000	0.61
hsa-miR-29c-3p	85.5	18.35	77.9	10.14	0.000	0.55
hsa-miR-30a-5p	32.7	2.24	11.7	0.53	0.000	0.24
hsa-miR-30b-5p	94.4	20.87	90.3	10.81	0.000	0.52
hsa-miR-30c-5p	79.0	6.79	66.9	3.53	0.000	0.52
hsa-miR-30d-5p	99.8	32.98	99.4	21.46	0.000	0.65
hsa-miR-30e-5p	46.6	3.03	30.5	1.58	0.000	0.52
hsa-miR-31-5p	14.5	10.05	37.0	15.68	0.000	1.56
hsa-miR-330-3p	46.5	2.99	61.0	4.69	0.000	1.57
hsa-miR-3609	45.9	2.57	18.8	0.81	0.000	0.31
hsa-miR-361-3p	11.5	1.36	4.5	0.56	0.000	0.41
hsa-miR-361-5p	88.3	11.15	70.8	4.32	0.000	0.39
hsa-miR-362-5p	33.4	3.63	13.0	2.34	0.000	0.64
hsa-miR-3651	99.0	55.13	98.7	35.97	0.000	0.65
hsa-miR-3653	94.1	13.36	87.0	7.12	0.000	0.53
hsa-miR-365a-3p	63.7	7.91	37.0	4.18	0.000	0.53
hsa-miR-374b-5p	29.4	6.75	6.5	1.99	0.000	0.29
hsa-miR-424-5p	33.3	4.08	13.6	2.50	0.000	0.61
hsa-miR-425-5p	81.2	9.86	74.7	5.34	0.000	0.54
hsa-miR-4284	100.0	1352.71	100.0	873.15	0.000	0.65
hsa-miR-429	66.3	12.28	49.4	6.86	0.000	0.56
hsa-miR-4492	12.2	1.20	20.1	1.97	0.013	1.65
hsa-miR-455-3p	14.8	5.00	7.8	2.24	0.001	0.45
hsa-miR-4681	3.5	0.70	8.4	1.45	0.024	2.06
hsa-miR-483-3p	41.5	9.94	33.1	3.80	0.002	0.38
hsa-miR-497-5p	23.3	1.51	7.1	0.44	0.000	0.29
hsa-miR-505-5p	8.5	0.50	3.9	0.32	0.006	0.63
hsa-miR-520d-3p	12.4	1.62	22.1	3.05	0.014	1.88
hsa-miR-532-3p	27.9	3.10	6.5	1.57	0.000	0.51
hsa-miR-532-5p	41.1	5.74	7.8	1.62	0.000	0.28
hsa-miR-590-5p	23.0	2.14	5.8	0.34	0.000	0.16
hsa-miR-625-5p	7.6	1.27	16.9	2.47	0.003	1.95
hsa-miR-6515-5p	27.4	1.14	35.7	1.79	0.010	1.56
hsa-miR-652-3p	19.5	2.50	5.8	1.12	0.000	0.45
hsa-miR-664a-3p	39.5	4.27	18.2	2.27	0.000	0.53
hsa-miR-664a-5p	93.0	11.72	81.8	6.73	0.000	0.57
hsa-miR-664b-3p	99.7	31.27	100.0	16.29	0.000	0.52
hsa-miR-664b-5p	99.7	59.42	98.7	30.99	0.000	0.52
hsa-miR-92a-3p	99.8	107.15	99.4	52.95	0.000	0.49
hsa-miR-92b-3p	11.2	1.03	8.4	0.48	0.042	0.47
hsa-miR-98-5p	34.5	3.59	9.1	1.29	0.000	0.36
hsa-miR-99a-5p	49.8	5.52	22.1	2.07	0.000	0.38
hsa-miR-99b-5p	44.0	5.10	31.8	3.33	0.001	0.65

¹Fold Change is Microsatellite unstable/microsatellite stable